Dr Ken Leung wins two Asian Core Program Lectureship Awards which will take him to China and Singapore to deliver a series of lectures


梁湛輝博士奪得兩項亞洲核心計劃講學獎,將赴內地和新加坡講學

Date: 14 Nov 2017 (Tuesday)

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Chemistry scholar wins Lectureship Awards

化學系學者獲頒講學獎

Dr Ken Leung, Associate Professor of the Department of Chemistry, was invited to deliver an oral presentation entitled “Controlling the Molecular Motion for Organocatalysis and Drug Delivery”, which won him two Asian Core Program Lectureship Awards at the 12th International Conference of Cutting-Edge Organic Chemistry in Asia held by Shanxi Normal University, Xian, Mainland China in November.

As the winner of the awards, Dr Leung will deliver an array of lectures in Mainland China and Singapore in the coming year. The awards reflect huge credit on Dr Leung’s research output, and demonstrate that his work on organic chemistry is well recognised by the selection committees in the two countries.

Dr Leung’s research combines the concepts of molecular machines and organic catalysts to generate specialty rotaxane dual catalysts with a fluorescence tag. Upon the addition of acid/base, the two catalysts can be reversibly “switched on and off” to synthesise the desired product exclusively from a mixture of starting materials. In another area, Dr Leung combines molecular machines and organic near-spherical dendrimers to look at the collective three-dimensional contraction-extension molecular motion of these nano-sized molecules. These novel hyper-branched macromolecules with mechanical bonds on every branching unit can bind with anti-cancer drugs and trigger an active drug release in acidic environments.

化學系副教授梁湛輝博士於11月在內地西安陝西師範大學舉行的第12屆亞洲尖端有機化學國際會議中獲邀發表「控制有機催化和藥物遞送的分子運動」研究項目,奪得兩項亞洲核心計劃講學獎。他明年將赴內地和新加坡各一星期講學。講學獎反映梁博士在有機化學方面的研究得到兩國遴選委員會的肯定。

梁博士的研究項目結合了分子機器與有機化學催化劑的概念,合成出一種特別的熒光輪烷雙有機催化劑。當改變反應體系中的酸鹼度,輪烷的雙催化效果可以「開關」,從混合起始材料中有效地合成出一種新的化合物。梁博士的另一研究項目結合了分子機器與有機樹狀分子創做出一種接近球形,可調控體積大小的分子機器。這種最新型高分子量,納米球形伸縮分子運動分子機器,可以成功運載抗癌藥,並在酸性環境中引發活性藥物釋放。